The Engenex™ Advanced Wound Therapy System is a refinement of negative pressure wound therapy (NPWT), which encourages healing of wounds in a manner that mimics normal acute wound healing.  The Engenex™ system promotes rapid tissue growth by imposing controlled strain, removing deleterious materials while maintaining a moist healing environment. 

At the heart of the Engenex™ dressing material is a novel technology, the Bio-Domes™ that promote granular tissue growth at lower, and therefore safer pressures than previously thought possible.  The Bio-Domes™ in the Engenex™ dressing are specially engineered structures that form a defined space above the surface of the wound.  This space will maintain its size and integrity in the presence of negative pressure and wound fluids and thus effectively impose strain on the underlying tissue. This action promotes unobstructed growth with less dressing integration into the wound.  Further, the structure allows the passage of wound fluids, which is essential for effective NPWT.  The material properties of the dressing permits moist wound healing, while encouraging the efficient removal of exudates.  The contact material will not absorb fluid.  It has been clinically shown that the Bio-Domes™ are effective at growing granular tissue in the base of a wound at a safe low negative pressure of 75 mmHg.

The collapsible packing portion of the Bio-Dome™ dressing is intended to effectively fill the wound, while permitting the efficient fluid transport of exudates.  The packing is specifically designed to resist collapse in a given direction to allow for preferred anatomic closure.  The anisotropic collapse characteristic of the Engenex™ dressing is tailored to perform in a manner that encourages wound healing that is supportive of the natural healing process.